Francine Shapiro Library

Francine Shapiro Library: EMDR Bibliography

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1. Gerardi, M., Rothbaum, B. O., Astin, M.C., & Kelley, M. (2010, June). Cortisol response following exposure treatment for PTSD in rape victims. Journal of Aggression, Maltreatment & Trauma, 19(4), 349-356. doi:10.1080/10926771003781297.

Language: English

Format: Journal

Abstract:
This study examined changes in salivary cortisol levels pre-to-post-treatment in adult female rape victims diagnosed with post traumatic stress disorder (PTSD) randomly assigned to be treated with either Prolonged Exposure Therapy or Eye Movement Desensitization and Reprocessing. Salivary cortisol was collected at baseline, session 3, and session 9. A significant decrease in salivary cortisol levels was observed in individuals classified as treatment responders in both treatment conditions. Findings suggest that successful exposure-based treatments for PTSD which result in trauma-related and depressive symptom reduction may impact the action of the hypothalamic-pituitary-adrenal axis as measured by changes in level of salivary cortisol from pre-to-post-treatment.

Keywords: Rape  Posttraumatic Stress Disorder  PTSD  

2. Heber, R., Kellner, M., & Yehuda, R. (2002, December). Salivary cortisol levels and the cortisol response to dexamethasone before and after EMDR:  A case report. Journal of Clinical Psychology, 58(12), 1521-1530. doi:10.1002/jclp.10102.

Language: English

Format: Journal

Abstract:
Trauma survivors with PTSD have been shown to have lower basal cortisol levels in the urine, plasma, and saliva than in trauma survivors without PTSD, nontraumatized mentally ill, or healthy subjects. We report on a case study in which we measured pre- and post-Eye Movement Desensitization and Reprocessing (EMDR) treatment salivary cortisol levels and salivary cortisol response to 0.50 mg of dexamethasone in a 41-year-old female with chronic PTSD symptoms. Our goal was to determine whether symptom improvement following trauma-focused treatment (EMDR) is associated with changes in basal salivary cortisol or in the cortisol response to dexamethasone administration. Our findings show moderate symptom improvement, an increase in basal cortisol levels, and a more attenuated cortisol hypersuppression in response to the dexamethasone suppression test following EMDR treatment. These results suggest the potential utility of including neuroendocrine measures in the assessment of treatment outcome in PTSD. [Author Abstract]

Keywords: Battery  Biologic Markers  Brief Psychotherapy  Case Report  Clinical Case Study  Cortisol  Dexamethasone Suppression Test  Empirical Study  Females  Legal Procedures  Middle Aged  Multiple Traumatic Events  Neuroendocrine Neuroendocrine Testing  Neuroendocrinology  Posttraumatic Stress Disorder  PTSD  Rape  Survivors  Treatment Effectiveness  

3. Resick, P., Monson, C., Griffin, M., Rothbaum, B., Rasmusson, A., & Shalev, A. (2006, November). Cortisol pre and posttreatment with EMDR or prolonged imaginal exposure in PTSD assault survivors. In Psychobiology and Treatment of PTSD. Symposium conducted at the 22nd annual meeting of the International Society for Traumatic Stress Studies Fall Conference, Hollywood, CA.

Language: English

Format: Conference

Abstract:
Psychobiological treatment of PTSD: This symposium will examine four CBT treatment studies with regard to biological markers. The questions here are whether pretreatment psychobiology or physiological responding can be used to predict treatment outcome, or whether they themselves change as a result of effective treatment.

Cortisol pre and posttreatment with EMDR or prolonged imaginal exposure in PTSD assault survivors: Many studies have noted increased cortisol production in trauma survivors with PTSD, but it is not clear whether effective treatment alters these responses. As part of a larger study, 60 female sexual assault survivors with PTSD began one of two types of cognitivebehavioral treatment (Prolonged Exposure (PE) or EMDR). Each treatment consisted of nine sessions. Sessions 1 and 2 included information gathering, trauma education, and therapy preparation. Sessions 3 through 9 consisted of processing traumatic memories and emotions via either imaginal exposure or EMDR.To examine potential cortisol changes over the course of treatment, salivary cortisol samples were collected at three time points during treatment. A baseline sample was taken at session 1, a second sample was taken at the start of the treatment portion of therapy (session 3), and a third sample was taken at the end of treatment (session 9). Of the original sample of 60 participants, 50 women completed treatment, and ten dropped out. Cortisol responses will be examined in treatment responders and non-responders as well as in treatment completers vs. treatment dropouts.

Keywords: Cortisol  Posttraumatic Stress Disorder  Prolonged Imaginal Exposure  Assault  PSTD  Survivors  Symposium  

4. Rothbaum, B. O., Astin, M., Gerardi, M., & Kelley, M. (2006, November). Cortisol pre-and post- treatment with EMDR or prolonged imaginal exposure in PTSD assault survivors. Presentation at the Annual Meeting of the Internatinal Society for Traumtic Stress Studies, Hollywood, CA.

Language: English

Format: Conference

Keywords: Assault  Posttraumatic Stress Disorder  Prolonged Imaginal Exposure  PTSD  Survivors  

5. van der Kolk, B. A., Hopper, J., & Spinazzola, J. (2004, November). Biological changes in arousal and cortisol following PTSD treatment. Symposium conducted (M. Olff, Chair) at the 20th annual meeting of the International Society of Traumatic Stress Studies, New Orleans, LA.

Language: English

Format: Conference

Abstract:
Effects of treatment of PTSD on psychobiological measures: It is well known that PTSD is associated with changes in several biological systems. However little research has been done on whether it is possible to “reset” these biological systems with effective psychotherapy of pharmacological therapy. This symposium will present data on neuroendocrine and neuroimaging outcome measures.
Biological changes in arousal and cortisol following PTSD treatment: This presentation will discuss the results of a controlled treatment outcome study comparing EMDR, fluoxetine and pill placebo and demonstrate how effective treatment resulted in changes in memory processes, utilizing the Traumatic Memory Inventrory. In the EMDR condition, but not fluoxetine, the change in traumatic memory towards an integrated narrative was linearly correlated with physiological arousal in response to script driven imagery. This presentation will also present the relationship between clinical improvement in the three conditions and change in the cortisol response to a dexamethasone challenge.

Keywords: Fluoxetine  Pill Placebo  Posttraumatic Stress Disorder  PSTD  Symposium