Francine Shapiro Library - EMDR Bibliography Links
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1. 宋磊 王振英 [Song Lei & Wang Zhen-Ying]. (2007, November). 舍曲林联合EMDR治疗抑郁症对照研究 [Sertraline treatment of depression combined EMDR research: A control study of sertraline combined with the EMDR in the treatment of depression]. 临床心身疾病，13（4） [Journal of Clinical Psychosomatic Disease, 13(4)].
Language: Chinese
Format: Journal
Abstract:
目的 探讨舍曲林联合眼动脱敏和再加工治疗对抑郁症的临床疗效及安全性.方法 将64例抑郁症患者随机分为两组各32例,均给予舍曲林治疗,研究组联合眼动脱敏和再加工治疗,疗程均为6w.于治疗前及治疗第1 w、2 w、6 w末采用汉密顿抑郁量表、临床总体印象量表评定临床疗效,副反应量表评定不良反应.结果 治疗6 w末研究组有效率87.5%,对照组为84.4%,两组差异无显著性(χ2=0.129,P＞0.05).汉密顿抑郁量表、临床总体印象量表评分,研究组治疗1 w末均较对照组下降显著(P均＜0.05),2 w末均较对照组下降极显著(P均＜0.01),6 w末差异均无显著性(P均＞0.05).两组不良反应均轻微(P＞0.05).结论 舍曲林联合眼动脱敏和再加工治疗治疗抑郁症疗效显著,起效更快,安全性高,依从性好.
Objective: To study the combined sertraline and reprocessing eye movement desensitization treatment for depression efficacy and safety. Methods 64 patients with depression were randomly divided into two groups, 32 cases were treated with sertraline treatment, the joint study group eyes Activity desensitization and reprocessing therapy, a course of 6w. in the first before treatment and 1 w, 2 w, 6 w end with Hamilton Depression Rating Scale, Clinical Global Impression Scale for assessment of clinical efficacy, adverse side effects rating scale reaction. Results 6 w end of study group and 87.5%, 84.4% of the control group, no significant difference between the two groups (χ2 = 0.129, P> 0.05). Hamilton Depression Rating Scale, Clinical Global Impression Scale scores 1 w at the end of treatment group was significantly decreased compared with the control group (P all <0.05), 2 w at the end than the control group decreased significantly (P all <0.01), 6 w at the end there was no significant difference (P all> 0.05) . two adverse reactions were mild (P> 0.05). Conclusion Joint eye sertraline desensitization and reprocessing therapy treatment of depression a significant effect, faster onset, high safety, good compliance.
Keywords: Control Study Depression Sertraline
Accuracy Verified: Yes
2. von Knorring, L., Thelander, S., & Pettersson, A. (2005, November 21-27). Behandling av angestsyndrom. En systematisklitteraturaversikt. SBUs sammanfattning och slutsatser [Treatment of anxiety syndrome: A systematic literature review. Summary and conclusions by the SBU]. Lakartidningen , 102(47), 3561-3562, 3565-3566, 3569.
Language: Swedish
Format: Journal
Abstract:
En rapport från det svenska rådet för medicinsk utvärdering (SBU) har gått igenom, klassificeras och utvärderas den vetenskapliga litteraturen om behandling av panik-syndrom, specifika fobier, social fobi, tvångssyndrom syndrom (OCD), generaliserat ångestsyndrom (GAD) och posttraumatiskt stressyndrom (PTSD). Översynen ingår behandling av barn, ungdomar och vuxna. Rapportens slutsats är att det finns effektiv behandling tillgänglig för alla ångest syndrom. Men i allmänhet, är effekten ofta måttliga och symtomen återkommer när behandlingen perioden avbryts. För vuxna, stödjer vetenskapliga bevis användning av paroxetin och sertralin för alla syndrom utom specifika fobier. För övriga SSRI-preparat Det finns också bevis för användning av Fluoxetin i OCD och PTSD, för fluvoxamin i social fobi och tvångssyndrom och för escitalopram i social fobi. Andra antidepressiva läkemedel med ett starkt vetenskapligt stöd är venlafaxin i social fobi och GAD, imipramin i panik syndrom och chlomipramine i panik syndrom och tvångssyndrom. Bland de psykologiska behandlingar, det finns vetenskapliga bevis för kognitiv beteendeterapi (KBT) för behandling av panik-syndrom, specifika fobier, social fobi, PTSD och GAD. Exponering, med eller utan andra psykoterapeutiska interventioner har vetenskapligt stöd för effekt vid paniksyndrom (både i termer av antalet panikattacker och agorafobi för), specifika fobier, tvångssyndrom och PTSD. Användning av ögonrörelser desensibilisering och upparbetning (EMDR) har vetenskapligt stöd för behandling av PTSD.
A report by the Swedish Council on Technology Assessment in Health Care (SBU) has reviewed, classified and evaluated the scientific literature on treatment of panic syndrome, specific phobias, social phobia, obsessive-compulsive syndrome (OCD), generalized anxiety syndrome (GAD) and post-traumatic stress disorder (PTSD). The review included treatment of children, adolescents and adults. The report concludes that there is effective treatment available for all anxiety syndromes. However in general, the effect is often moderate and symptoms reappear when the treatment period is discontinued. For adults, scientific evidence supports the use of paroxetine and sertraline for all syndromes except specific phobias. For the other SSRI's there is also evidence for the use of fluoxetin in OCD and PTSD, for fluvoxamine in social phobia and OCD and for escitalopram in social phobia. Other antidepressant drugs with a strong scientific support is venlafaxin in social phobia and GAD, imipramin in panic syndrome and chlomipramine in panic syndrome and OCD. Among psychological treatments, there is scientific evidence for cognitive behavior therapy (CBT) for treatment of panic syndrome, specific phobias, social phobia, PTSD and GAD. Exposure, with or without other psychotherapeutic interventions, has scientific support for efficacy in panic disorder (both in terms of number of panic attacks and for agoraphobia), specific phobias, OCD and PTSD. Use of eye movement desensitization and reprocessing (EMDR) has scientific support for treatment of PTSD.
Keywords: Review
Accuracy Verified: Yes
3. Sharpless, B. A., & Barber, J. P. (2011). A clinician’s guide to PTSD treatments for returning veterans. Professional Psychology: Research and Practice, 42(1), 8–15. doi:10.1037/a0022351.
Language: English
Format: Journal
Abstract:
What options are available to mental health providers helping clients with posttraumatic stress disorder
(PTSD)? In this paper we review many of the current pharmacological and psychological interventions
available to help prevent and treat PTSD with an emphasis on combat-related traumas and veteran populations.
There is strong evidence supporting the use of several therapies including prolonged exposure (PE), eye
movement desensitization and reprocessing (EMDR), and cognitive processing therapies (CPT), with PE
possessing the most empirical evidence in favor of its efficacy. There have been relatively fewer studies of
nonexposure based modalities (e.g., psychodynamic, interpersonal, and dialectical behavior therapy perspectives),
but there is no evidence that these treatments are less effective. Pharmacotherapy is promising
(especially paroxetine, sertraline, and venlafaxine), but more research comparing the relative merits of
medication vs. psychotherapy and the efficacy of combined treatments is needed. Given the recent influx of
combat-related traumas due to ongoing conflicts in Iraq and Afghanistan, there is clearly an urgent need to
conduct more randomized clinical trials research and effectiveness studies in military and Department of
Veterans Affairs PTSD samples. Finally, we provide references to a number of PTSD treatment manuals and
propose several recommendations to help guide clinicians’ treatment selections.
Keywords: Posttraumatic Stress Disorder Psychotherapy Psychopharmacology PTSD
Accuracy Verified: Yes
4. Turner, S. (2005, November). Drug treatments in the management of PTSD. Symposium conducted (S. Turner, Chair) at the 21st annual meeting of the International Society for Traumatic Stress Studies, Baltimore, MD.
Language: English
Format: Conference
Abstract:
The UK National Institute for Clinical Excellence
Guidelines on PTSD: Based on rigorous meta-analysis, detailed literature review and two public
consultations, the national guidelines for the assessment, prevention and
treatment of PTSD in the UK will be presented in this symposium on behalf
of the Guideline Development Group.
Drug treatments in the management of PTSD: Drug treatments are increasingly used in the management of PTSD and have
been supported by a number of recent reviews although there have been
increasing concerns about their safety. Recent guidance has been issued in
the UK by the Regulatory Agency concerning the use of SSRI drugs in people
of all ages, but especially in children and young adults. In a meta-analysis
of the clinical trial literature for PTSD, following a rigorous bibliographic
search, 26 RCTs meeting strict criteria were identified. Data on two hitherto
unpublished trials of sertraline were available for inclusion. This review highlights
the methodological issues involved in comparing drug trials and trials
of psychological therapies. Nonetheless, meta-analysis demonstrates that
drug treatments for PTSD are probably more disappointing than hitherto
believed. Only five drugs emerged with recommendations for use. One of
these has a reliable if modest effect (paroxetine). The other four are included
on the basis of small single trial reports. Although there are clear indications
for drug treatments, in general there should be an increasing emphasis on
ensuring that trauma-focused psychological treatments (CBT and EMDR) are
widely available, delivered by competent practitioners, and easily accessible
in a timely fashion in primary and secondary care settings.
Keywords: Drug Treatment Posttraumatic Stress Disorder PTSD Symposium
Accuracy Verified: No
5. Arnone, R., Orrico, A., D'Aquino, G., & Di Munzio, W. (2012, March-April). EMDR e terapia psicofarmacologica nel trattamento del disturbo da stress post-traumatico [EMDR and psychopharmacological therapy in the treatment of the post-traumatic stress disorder]. Rivista di Psichiatria, 47(Supplement 1), 8-11. doi:10.1708/1071.11732 .
Language: Italian
Format: Journal
Abstract:
Questo studio si propone di valutare l’efficacia di due diversi trattamenti nella cura del disturbo da stress post-traumatico (PTSD): la terapia psicofarmacologica, attraverso l’utilizzo di serotoninergici, e l’EMDR. Metodo. Sono stati utilizzati due gruppi indipendenti ai quali venivano somministrati due trattamenti differenti: il trattamento con sertralina per il gruppo assegnato alla terapia psicofarmacologica; il trattamento con sedute monosettimanali di EMDR per l’altro gruppo. Per la valutazione dei sintomi del PTSD è stata utilizzata la Clinician-Administered PTSD Scale (CAPS). L’assegnazione dei soggetti ai due gruppi è stata randomizzata. Risultati. I risultati confermano precedenti studi riportati in letteratura, evidenziando l’efficacia sia dell’EMDR sia della sertralina nel migliorare la sintomatologia post-traumatica e i livelli di sofferenza soggettiva. Tuttavia il numero di soggetti che al termine della condizione sperimentale non rientrava più nei criteri diagnostici del PTSD è risultato nettamente superiore nel gruppo trattato con EMDR. Conclusioni. Data la differenza nei due gruppi, a favore di quello trattato con EMDR, del numero di soggetti che possono essere considerati responder e che, come tali, non soddisfano più i criteri del PTSD al termine della condizione sperimentale, possiamo affermare che l’ipotesi per cui l’EMDR è un trattamento più efficace rispetto al trattamento psicofarmacologico è stata confermata. Questo dato potrebbe stimolare ricerche future con campioni più numerosi che indaghino anche l’efficacia a lungo termine.
This study evaluates the efficacy of two different treatment for post-traumatic stress disorder (PTSD): the psychopharmacological therapy, with a SSRI drug, and EMDR. Method. Two indipendent groups have been administered two different treatments: the treatment with sertraline to the group for psychopharmacological therapy; the treatment with one-week sessions of EMDR to the other group. For the evaluation of the symptoms of PTSD has been used the Clinician-Administered PTSD Scale (CAPS). The inclusion of the subjects in the two groups has been absolutely random. Results. The results confirm previous studies available in literature, pointing out the efficacy of EMDR and of sertraline in improving the post-traumatic symptomatology and the levels of subjective sufference. But the number of subjects which at the end of the study didn't satisfy any more the criteria for PTSD has been absolutely greater in the group treated with EMDR. Conclusions. The study confirms the hypothesis of EMDR as a more efficacious treatment for PTSD compared to psychopharmacological therapy. This result could be a stimolous for further research with greater groups to investigate also the long term efficacy.
Keywords: CAPS Clinician-Administered PTSD Scale Efficiacy PTSD, Sertraline
Accuracy Verified: Yes
6. Tavanti, M., Bossini, L., Calossi, S., Marino, D. Vatti, G., Galli, R., Pieraccini, F. & Castrogiovanni, P. (2008, August-September). P.1.e.006 Sertraline versus eye movement desensitization and reprocessing (EMDR): Effects on hippocampal volumes and PTSD symptoms. In Papers of the 21st European College of Neuropsychopharmacology Congress, in European Neuropsychopharmacology, 18(Supplement 4), S262. doi:10.1016/S0924-977X(08)70339-0.
Language: English
Format: Conference
Keywords: Sertraline
Accuracy Verified: Yes
7. Cahill, P. C., Pontoski, K., & D’Olio, C. M. (2005, September). Posttraumatic stress disorder and acute stress disorder II: Considerations for treatment and prevention. Psychiatry, 2(9), 34-46.
Language: English
Format: Journal
Abstract:
Posttraumatic stress disorder is a common and often chronic and disabling anxiety disorder that can develop after exposure to highly stressful events characterized by actual or threatened harm to the self or others. This is the second of two invited articles summarizing the nature and treatment of PTSD and the associated condition of acute stress disorder (ASD). The present article reviews evidence for the efficacy of psychological and pharmacological treatments for PTSD and ASD. In summary, cognitive behavior therapy (CBT) has been found efficacious in the treatment of chronic PTSD as well as the treatment of ASD/prevention of PTSD. The selective serotonin reuptake inhibitors, sertraline, paroxetine, and fluoxetine, have been found efficacious in the treatment of chronic PTSD, with sertraline and paroxetine receiving the FDA indication for this condition. There is less evidence for efficacious medications in the treatment of ASD/prevention of PTSD. At present, hydrocortisone and propranolol show the greatest promise. Limitations of these treatments, including dropout and a significant number of patients showing no or only partial response, are discussed as well as issues related to selecting among efficacious treatments.
Keywords: ASD Acute Stress Disorder Posttraumatic Stress Disorder PTSD
Accuracy Verified: Yes
8. Davidson, J. R. T., Stein, D. J., Shalev, A.Y., & Yehuda, R. (2004, Spring). Posttraumatic stress disorder: Acquisition, recognition, course, and treatment. Journal of Neuropsychiatry and Clinical Neuroscience, 16(2), 135-147. doi:10.1176/appi.neuropsych.16.2.135.
Language: English
Format: Journal
Abstract:
Following exposure to trauma, a large number of survivors will develop acute symptoms of posttraumatic stress disorder (PTSD), which mostly dissipate within a short time. In a minority, however, these symptoms will evolve into chronic and persistent PTSD. A number of factors increase the likelihood of this occurring, including characteristic autonomic and hypothalamic-pituitary-adrenal axis responses. PTSD often presents with comorbid depression, or in the form of somatization, both of which significantly reduce the possibilities of a correct diagnosis and appropriate treatment. Mainstay treatments include exposure-based psychosocial therapy and selective serotonin reuptake inhibitors, such as paroxetine and sertraline, both of which have been found to be effective in PTSD. This paper looks at the course of PTSD, its disabling effect, its recognition and treatment, and considers possible new research directions.
Keywords: Comorbidity Posttraumatic Stress Disorder PTSD Recognition and Treatment SSRIs
Accuracy Verified: Yes
9. Tavanti, M., Bossini, L., Calossi, S., Lombardelli, A., Polizzotto, N., Vatti, G., Galli, R., Pieraccini F., & Castrogiovanni, P. (2008, Febbraio). Sertralina vs EMDR: Effetti sul volume ippocampale [Sertraline vs. EMDR: Effects on hippocampal volume]. Poster presentato al XII Congresso SOPSI (Società Italiana di Psicopatologia), Roma, Italia.
Language: Italian
Format: Conference
Abstract:
Molti dati sperimentali hanno mostrato che la terapia farmacologica
con SSRI può incrementare il volume dell’ippocampo,
invece il solo studio che ha investigato gli effetti di un tipo
di psicoterapia (TEB, Terapia Eclettica Breve) non ha evidenziato
alcuna efficacia sul volume ippocampale 1. Scopo
del nostro studio è valutare gli effetti del trattamento con EMDR
(Eye Movement Desensitization and Reprocessing) sul
volume ippocampale, sui sintomi e sulle performances mnesiche
di pazienti con Disturbo Post-Traumatico da Stress
(DPTS). La EMDR è una terapia la cui efficacia nel DPTS è
stata dimostrata in numerosi studi sperimentali.
Sono stati selezionati 12 soggetti drug-free con diagnosi di
DPTS alla SCID-P, senza comorbidità psichiatrica.
Ogni soggetto reclutato è stato sottoposto alla prima visita
(Tempo 0, Drug-Free) ad una indagine psicometrica (tramite
DTS), ad una indagine neuropsicologica (tramite una batteria
di test) e alla misurazione dei volumi cerebrali tramite
Risonanza Magnetica.
Successivamente, i 12 soggetti sono stati attribuiti in maniera
random a due diversi protocolli terapeutici. Sei soggetti
hanno effettuato 12 sedute di EMDR della durata di 1,5
ore, mentre sei soggetti sono stati trattati con 100 mg di sertralina.
Dopo il trattamento (Tempo 1, Post-Terapia) i soggetti sono
stati nuovamente sottoposti alle indagini effettuate al Tempo
0.
La seconda valutazione al Tempo 1 è stata effettuata dopo
tre mesi nei soggetti trattati con EMDR e dopo 6 mesi nei
soggetti trattati con la sertralina, in base ai tempi medi necessari
per la remissione cilinica del DPTS riportati in letteratura
per i due presidi terapeutici.
In questo studio verranno presentati i dati relativi alle differenze
volumetriche, ai miglioramenti clinici e alla performance
mnesica nei due gruppi di soggetti (soggetti sottoposti
ad EMDR e soggetti trattati con sertralina) e un dettagliato
confronto dei risultati ottenuti.
Many experimental data have shown that drug therapy
with SSRIs may increase the volume of the hippocampus,
Instead the only study that has investigated the effects of a type
psychotherapy (TEB, Brief Therapy Eclectic) showed no
no effect on hippocampal volume 1. Purpose
of our study was to evaluate the effects of treatment with EMDR
(Eye movement desensitization and reprocessing) on
hippocampal volume, symptoms and performance mnesic
of patients with Post-Traumatic Stress Disorder
(PTSD). The EMDR is a therapy whose efficacy in PTSD is
been demonstrated in numerous experimental studies.
Were selected 12 subjects with a diagnosis of drug-free
PTSD in the SCID-P, without psychiatric comorbidity.
Each recruited subject was submitted to the first visit
(Time 0, Drug-Free) at a psychometric investigation (by
DTS), a neuropsychological investigation (using a battery
test) and measurement of brain volume through
Magnetic Resonance Imaging.
Subsequently, 12 subjects have been allocated
random to two different treatment protocols. Six subjects
have carried out 12 sessions of EMDR duration of 1.5
hours, while six patients were treated with 100 mg of sertraline.
After treatment (Time 1, Post-Therapy) subjects are
were again subjected to the investigations made at the time
0.
The second evaluation at Time 1 was made after
three months in subjects treated with EMDR and after 6 months in
subjects treated with sertraline, based on the average time needed
cylinder for the remission of PTSD reported in the literature
for the two therapeutic aids.
In this study will be presented data on differences
displacement, the clinical improvements and performance
mnesic in the two groups of subjects (subjects
EMDR for patients treated with sertraline) and a detailed
comparison of results.
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Keywords: Hippocampal Volume Poster Sertraline
Accuracy Verified: Yes