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Your Results - you searched for the keyword Electrophysiological Changes 6 Results
1. Haour, F. (2009, June). Brain source imaging of the alpha rhythm in PTSD patients using the MEG technique. In K. Zaal (Chair), Research). Symposium conducted at the annual meeting of the EMDR Europe Association, Amsterdam, the Netherlands.
Language: English
Format: Conference
Abstract:
In anxiety disorders, such as PTSD, brain imaging has demonstrated local modifications of functional activities using various techniques. In the present study the direct neuronal activities were measured in delta, theta and beta frequencies, using Magnetoencephalagraphy (MEG) which provides very fast temporal response. The technique is neither invasive nor stressful for the patients.
Nineteen female volunteers with DSM-IV PTSD were included in the study. The protocol was a script-driven imagery provocation test, achieved with the patients sitting in the MEG apparatus. The scenarios, specific for ach patient, were composed of 4 active conditions: neutral image (N) traumatic memory (T), traumatic memory suppression (TS) and positive image (P) corresponding to 3 minutes where the patient had to imagine the corresponding sequence with eyes closed Measures of heat rate and subjective disturbance (SUD) were measured during the recoding. The MEG data were analysed in the source domain using a spatial filtering approach. Measurement of electrophysiological waves of various rhythms: delta: 1-4 Hetz (Hz), theta: 4.8-5.8 Hz, alpha: 8-12 Hz and beta: 12-25 Hz was obtained. Anatomical information was from MRI imaging.
Signal of activation during trauma recall (T-N) were limited to the delta and theta waves and mainly found in the left hemisphere (visual, orbitofrontal and dorsolateral prefrontal and temporal gyrus (BA 8-9-10-11, 18-19, 22, 28) and in the right supra marginal gyrus (Wernicke BA 40).
Signal of inhibition during trauma recall (T-N) were found mainly in the left hemisphere, in the delta, alpha and beta waves (visual, orbitofrontal, dorsolateral prefrontal and temporal gyrus (BA 8-9-10-11, 18-18, 22, 28), cingular cortex (BA 23-24, 31, 32), insula (BA 13) and Broca visual cortex (BA 18-19, 43-44).
In conclusion trauma recall mainly induces a hypoactivation in the ventromedial prefrontal cortex and in the cingular cortices, structures linked to the experience and regulation of emotions.
Keywords: Alpha Rhythm Brain Imaging MEG Technique Posttraumatic Stress Disorder PTSD Research Symposium
Accuracy Verified: Yes
2. Haour, F. (2010, June). Brain source imaging using magnetoencephalography (MEG): Modifications in various rhythms during memory recall, in PTSD patients. In Research. Symposium conducted at the annual meeting of the EMDR Europe Association, Hamburg, Germany.
Language: English
Format: Conference
Abstract:
In anxiety disorders, such as PTSD, brain imaging has demonstrated local modifications of functional activities using various techniques. In the present study the direct neuronal activities were measured in delta, theta and beta frequencies, using Magnetoencephalagraphy (MEG) which provides very fast temporal response. The technique is neither invasive nor stressful for the patients.
Nineteen female volunteers with DSM-IV PTSD were included in the study. The protocol was a script-driven imagery provocation test, achieved with the patients sitting in the MEG apparatus. The scenarios, specific for ach patient, were composed of 4 active conditions: neutral image (N) traumatic memory (T), traumatic memory suppression (TS) and positive image (P) corresponding to 3 minutes where the patient had to imagine the corresponding sequence with eyes closed Measures of heat rate and subjective disturbance (SUD) were measured during the recoding. The MEG data were analysed in the source domain using a spatial filtering approach. Measurement of electrophysiological waves of various rhythms: delta: 1-4 Hetz (Hz), theta: 4.8-5.8 Hz, alpha: 8-12 Hz and beta: 12-25 Hz was obtained. Anatomical information was from MRI imaging.
Signal of activation during trauma recall (T-N) were limited to the delta and theta waves and mainly found in the left hemisphere (visual, orbitofrontal and dorsolateral prefrontal and temporal gyrus (BA 8-9-10-11, 18-19, 22, 28) and in the right supra marginal gyrus (Wernicke BA 40).
Signal of inhibition during trauma recall (T-N) were found mainly in the left hemisphere, in the delta, alpha and beta waves (visual, orbitofrontal, dorsolateral prefrontal and temporal gyrus (BA 8-9-10-11, 18-18, 22, 28), cingular cortex (BA 23-24, 31, 32), insula (BA 13) and Broca visual cortex (BA 18-19, 43-44).
In conclusion trauma recall mainly induces a hypoactivation in the ventromedial prefrontal cortex and in the cingular cortices, structures linked to the experience and regulation of emotions.
Keywords: Magnetoencephalography MEG Memory Recall Posttraumatic Stress Disorder PTSD Research Rhythms Symposium
Accuracy Verified: Yes
3. Grbesa, G., Stankovic, D., & Simonovic, M. (2008, June). Electrophysiological changes during EMDR treatment. Presentation at the annual meeting of the EMDR Europe Association, London, England.
Language: English
Format: Conference
Abstract:
Efficiency of the EMDR procedure is based on a presumption of neuropsychological changes in therapeutically
process. The aim of the investigation is scanning and gives evidence of electroactivity changes, during the process
and after finishing it. Method: We have recorded a continual polygraph EEG, before, in time and after EMDR
therapy, in patient who had PTSD. Results: The EEG before treatment showed background activity low voltage
20-30 μV, 12-13 Hz frequency, bioccipital, without pathological activity. Patient had prominent vegetative
symptoms (anxiety, heart rate 100/min). Background activity after treatment showed voltage about 50 μV,
frequency dominant 12 Hz which showed reduction of anxiety, and reduction of vegetative disturbance.
Keywords: Electrophysiological Changes
Accuracy Verified: Yes
4. Grbesa, G., Simonovic, M., & Jankovic, D. (2010, April). Electrophysiological changes during EMDR treatment in patients with combat-related PTSD. Annals of General Psychiatry, 9(Supplement 1), S209. doi:10.1186/1744-859X-9-S1-S209.
Language: English
Format: Journal
Abstract:
1st International Congress on Neurobiology and Clinical Psychopharmacology and European Psychiatric Association Conference on Treatment Guidance
Background
Efficiency of the EMDR procedure is based on a presumption of neuropsychological changes in therapeutic process.The aim of the investigation is to scann and give evidence of electroactivity changes, during the process of EMDR procedure and after finishing it.
Materials and methods
We have recorded a continual polygraph EEG, before, during and after EMDR therapy, in patient with combat-related PTSD.
Results
Before the treatment, EEG recorded basic activity of low voltage (attenuation) of 20 μV, frequency of beta range (17-26 Hz), bioccipital, with no pathologic activity. Patient had prominent vegetative symptoms (anxiety, heart rate 100/min). Background activity immediately after the treatment records the amplitude values of around 50 μV, frequency of around 11-12 Hz. After the end of the treatment background activity possesses the amplitude value of about 37 μV, holding the persistence in frequency.
Conclusions
If the EMDR treatment is successful, sudden increase of amplityde activity is noted imensly. This sharp border line, which signifies normal activity, appears in 2-3 seconds affter the desensitize phase. The investigation suggest that from neurophysiological point of view, cortex (in EMDR procedure), works according to the principle "all or nothing". If there is processing of traumatic memory, the activity gets completly normal. If the therapy is not successful, there are numerous artefacts, because of increased muscle activity. This kind of activity, in our investigation is marked as "Artefact therapy".
The results, indicate maintaining low level of amplitude values of electrocortical activities during the treatment, as well as increase after successful treatment. The increase of amlitude is corelated to decrease of anxiety after the successful treatment.
Acknowledgements
The results, indicate maintaining low level of amplitude values of electrocortical activities during the treatment, as well as increase after successful treatment. The increase of amlitude is corelated to decrease of anxiety after the successful treatment.
References
EEG Asymmetry and its Clinical Correlates in PTSD, Steven Silverstein, Stewart Shankman Lea Williams, Patrick Hopkinson, Richard Bryant
Keywords: Combat Electrophysiological Change Posttraumatic Stress Disorder PTSD
Accuracy Verified: Yes
5. Raynaud, P., Boxus, A., Renoir, V., & Sanchez, S. (2012, January). P-975 - From mind to brain: Event-related potentials and EMDR treatment of post-traumatic stress disorder. European Psychiatry, 27(Supplement 1), 1-1. doi:10.1016/S0924-9338(12)75142-8.
Language: English
Format: Journal
Abstract:
Introduction: Eye movement desensitization and reprocessing (EMDR) is a relevant technique to improve post-traumatic stress disorder (PTSD) symptoms. Objectives: To compare the electrophysiological profile of patients suffering post traumatic stress disorder before and after EMDR treatment. Aims: The authors are in search of a specific event-related brain potentials profile for post-traumatic stress disorder (PTSD). Methods: Eight patients suffering from post-traumatic stress disorder (PTSD) following a severe traumatic event, were assessed with event-related brain potentials (ERPs) in a modified oddball paradigm containing auditory standard, target, and novel tones. ERPs were assessed before and after a treatment session using the eye movement desensitization and reprocessing method. Results: Psychometric assessment revealed a marked improvement of the PTSD symptoms after treatment. Compared to a control group that underwent sham treatment, ERPs of the patients showed morphological changes in the post-treatment recording, suggesting a reduced orienting to novel stimuli and reduced arousal level after the treatment. Conclusions: EMDR therapy provides clinical improvement and event-related potentials changes that could be used in clinical practice as an interesting marker to assess diagnosis and successful treatment of PTSD.
Keywords: Event-Related Posttraumatic Stress Disorder PTSD
Accuracy Verified: Yes
6. Lamprecht, F., Sack, M., Lempa, W., & Eickhoff-Fels, S. (2001). Psychophysiological activation via trauma script in PTSD patients and matched healthy controls and its reversal after succesful treatment. Presentation at the annual meeting of the German Society for Psychotraumatology.
Language: English
Format: Conference
Abstract:
Purpose: It is well known that hyperarousal in PTSD patients leads to an increase in heart rate to trauma related stimuli. The purpose of this study was to see if this peripheral physiological activation in PTSD patients by a trauma script can be reversed by successful trauma treatment including EMDR (Eye Movement Desensitization and Reprocessing).
Methods:
12 PTSD patients fulfilling DSM IV criteria with 52.6 mean level of the impact of event scale (IES) and 8.1 of the subjective unit of distress (SUD) were compared to 12 matched healthy controls (IES level 23, SUD level 4.8). Glued electrodes were placed according to published guidelines for electrophysiological research on thorax (ECG) and palmar skin of the left (non dominant) hand (SCL). Psychophysiological data (heart rate and skin conductance) were recorded continually and stored on a PC card during three conditions: neutral, relaxation and trauma script. In the patient group the procedure was repeated after finishing treatment.
Results: The patient group and control group did not differ in the baseline heart rate, however, the stimulation by the trauma script in the PTSD patients was significant in the mean 15.6 (T-2.88) (p < 0.01) increase in heart rate and in the control group 1.6 not significant (the script here was derived from the worst life event). There was a wide variation in the patient group with three patients without any reaction. In those with a strong reaction after trauma script, successful treatment was accompanied by a decline in heart rate response after trauma script, which remained stable during 6 months follow-up. SCL data did not show any consistent relationship. Since this is an ongoing study with increasing numbers and further analysis, additional data will be given during presentation. A decline of the SUD level to 2.3 and within the IES-score to 21 at the three months follow-up measurement was also significant (p < 0.01).
Keywords: Posttraumatic Stress Disorder Psychophysiological Activation PSTD Trauma Script
Accuracy Verified: Yes


